Authors:
Zoran Nenadić,
Bijoy K. Ghosh,
Volume: 1, Page 1776 Paper number 2401
Abstract:
Movements of human arm in a horizontal plane are very stereotyped in
the sense that the corresponding paths are mainly straight lines and
the velocity profiles are ``bell-shaped like'' functions. A dynamics
of two link model of the human arm has been studied with the goal of
synthesizing the torques which accomplish the desired transfer. For
that purpose a set of parameters which describes the desired transition
(initial position, final position, peak velocity, etc.) is chosen randomly
according to a certain distribution. The parameters of the desired
trajectory as well as the system variables (angles and angular velocities)
are encoded using populations of different number of neurons, usually
100-150. The underlying mathematics including integration, differentiation
and other algebraic relationships, has been done at the level of neuronal
activity. Finally, the driving torques are generated from the corresponding
activities using an optimal decoding rule.
Authors:
Petter Ögren,
Clyde F. Martin,
Volume: 1, Page 1782 Paper number 2503
Abstract:
Our goal is to calculate optimal vaccination patterns for a rapidly
spreading disease in an urbanized highly mobile population. The goal
being to determine if vaccination can effect a disease for which there
is low immunity in the population. Different types of structured SIR
models are investigated. We construct a model appropriate for a traveling
urbanized population and introduce a control in terms of a vaccination
program. Linear constraints, a quadratic cost on the control and
a linear cost on the number of infected are imposed. In this setting
we calculate optimal vaccination patterns using the maximum principle
of Pontryagin.
Authors:
Alan Barhorst,
Lawrence Schovanec,
Volume: 1, Page 1788 Paper number 2501
Abstract:
This paper provides a continuum analysis of skeletal elastic structures
in which loading conditions are derived from neural-musculotendon dynamics.
Forward dynamic simulations of human motion are based on an ensemble
of articulating segments controlled by Hill-type musculotendon actuators.
The joint torques and reaction forces as predicted by this analysis
determine loading conditions for the stress analysis of the segmental
links which are modeled as hybrid parameter systems. This approach
accounts for both the rigid body motions of the articulating links
and the elastic deformations that represent the continuum effects in
the bone. Although the methods in this paper are readily extended
to general multi-link segmental models, simulations for the arm-shoulder
complex are presented in order to illustrate the method.
Authors:
Manjula S. Sugathadasa,
Wijesuriya P. Dayawansa,
Clyde F. Martin,
Volume: 1, Page 1793 Paper number 2404
Abstract:
A dynamic model representing the pursuit eye movement is studied here.
It is known that feedback control is used in this type of eye movement.
A representative feedback control law is designed and simulations are
carried out to demonstrate its effectiveness.
Authors:
Yih-Choung Yu,
J. Robert Boston,
Marwan A. Simaan,
James F. Antaki,
Volume: 1, Page 1799 Paper number 2504
Abstract:
Maximum ventricular elastance, E_MAX, is a reliable quantitative index
of the contractial state of the ventricle. It is a strong candidate
to determine the healthy status of the patient's heart. However, estimating
E_MAX usually requires invasive pressure and flow sensors, which only
can be performed under certain clinical facility. If an indirect index
of E_MAX can be identified using measurements from a ventricular assist
device (VAD) without any indwelling sensor, this would facilitate an
effective way to monitor the healthy condition of the patient's heart
while the patient is under VAD support. This index can also be used
to control the VAD to gradually wean the patient from the mechanical
circulatory support. In this paper, three possible indices, systemic
vascular resistance, maximum VAD inflow acceleration rate, and the
maximum VAD inflow acceleration rate during heart ejection, were evaluated
as a representation of E_MAX using Novacor VAD volume and mean arterial
pressure measurements from a computer simulation. The maximum VAD inflow
acceleration rate during heart systole showed a strong correlation
to the E_MAX regardless the variation of native heart rate, and thus
can be used as an E_MAX index.
Authors:
Jonas Carlson,
Rolf Johansson,
S. Bertil Olsson,
Volume: 1, Page 1804 Paper number 2505
Abstract:
The atrial activity of the human heart is normally visible in the ECG
as a P-wave. In patients with intermittent atrial fibrillation, a different
P-wave morphology can sometimes be seen, indicating atrial conduction
defects. The purpose of this study was to develop a method to discriminate
between such P-waves and normal ones. 20 recordings of each type were
used in a classification which, based on impulse response analysis
of the P-wave and linear discrimination between various parameters,
produced a correct classification in 37 of the 40 recordings (sensitivity
95%, specificity 90%).
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